Advancing Precision Medicine for Pediatric Brain and Spinal Cord Tumors
Advances in molecular diagnostics are changing how clinicians diagnose and treat pediatric brain and spinal cord tumors.
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Pediatric CNS tumor classification has shifted from morphology alone to an integrated approach combining histopathology and molecular profiling.
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Precision medicine integrates imaging, pathology, molecular findings and patient-specific characteristics to characterize each child’s tumor.
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Next-generation sequencing, DNA methylation profiling and germline testing can refine diagnosis, inform prognosis and guide treatment decisions.
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Phoenix Children’s molecular tumor board brings specialists together to interpret clinical, imaging, pathology and molecular data.
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Phoenix Children’s is researching liquid biopsy approaches that may provide molecular evidence of residual disease earlier than MRI.
