IgG4-related autoimmune pancreatitis mimicking pancreatic carcinoma: a case report - Takeaways - MDSpire

IgG4-related autoimmune pancreatitis mimicking pancreatic carcinoma: a case report

  • By

  • Zejun Lu

  • Lijuan Wang

  • Ping Lu

  • Shangchao Cao

  • Bin Liu

  • Lei Li

  • Zhiqiang Jiang

  • Haiqiang Chu

  • Yingrong Xie

  • Jingbo Kang

  • June 18, 2026

  • 0 min

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  • 1

    A 59-year-old woman was diagnosed with IgG4-related autoimmune pancreatitis after initial suspicion of pancreatic cancer due to imaging findings.

  • 2

    Serum IgG4 levels were extremely elevated at 10,022 μg/mL, aiding in the diagnosis of autoimmune pancreatitis.

  • 3

    An ultrasound-guided biopsy revealed benign ductal epithelium, confirming the absence of pancreatic adenocarcinoma.

  • 4

    The patient was treated with oral methylprednisolone, leading to normalization of serum IgG4 and CA19-9 levels over one year.

  • 5

    This case highlights the importance of considering IgG4-related autoimmune pancreatitis in the differential diagnosis of pancreatic masses.

Original Source(s)

IgG4-related autoimmune pancreatitis mimicking pancreatic carcinoma: a case report

  • by Zejun Lu, Lijuan Wang, Ping Lu, Shangchao Cao, Bin Liu, Lei Li, Zhiqiang Jiang, Haiqiang Chu, Yingrong Xie, Jingbo Kang

  • June 18, 2026

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