Clinical characteristics and factors associated with in-hospital mortality in patients with Stenotrophomonas maltophilia infection: a single-center retrospective cohort study - Takeaways - MDSpire
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Clinical Features and Determinants of In-Hospital Mortality in Patients with Stenotrophomonas maltophilia Infections: A Retrospective Cohort Analysis from a Single Center

  • By

  • Hanli Wang

  • Min Xing

  • Haoyu Ji

  • Yusheng Cheng

  • Shuhui Hu

  • Guofeng Wang

  • Susheng Zhou

  • Yonghui Han

  • Bohan Zhang

  • Lei Zha

  • Qinghai You

  • August 21, 2026

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  • 1

    The study analyzed 458 inpatients with confirmed Stenotrophomonas maltophilia infections from June 2023 to July 2025.

  • 2

    In-hospital mortality was 11.8%, with non-survivors exhibiting higher age, comorbidity, and severe clinical characteristics.

  • 3

    Age and Charlson Comorbidity Index were independently associated with mortality, while mechanical ventilation's association was not statistically significant.

  • 4

    Previous carbapenem exposure did not significantly affect mortality, suggesting it may indicate underlying disease complexity.

  • 5

    The appropriateness of initial empirical antimicrobial therapy was not independently linked to survival after adjusting for severity factors.

Original Source(s)

Clinical characteristics and factors associated with in-hospital mortality in patients with Stenotrophomonas maltophilia infection: a single-center retrospective cohort study

  • by Hanli Wang, Min Xing, Haoyu Ji, Yusheng Cheng, Shuhui Hu, Guofeng Wang, Susheng Zhou, Yonghui Han, Bohan Zhang, Lei Zha, Qinghai You

  • August 21, 2026

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