Lack of SARS-CoV-2 Detection in Placental Tissue Following Maternal COVID-19 Infection - Takeaways - MDSpire

Lack of SARS-CoV-2 Detection in Placental Tissue Following Maternal COVID-19 Infection

  • By

  • Shelli F. Farhadian

  • Benjamin Orlinick

  • Kristin M. Milano

  • Dilgash Mekael

  • Harvey J. Kliman

  • April 22, 2026

  • 0 min

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  • 1

    SARS-CoV-2 infection during pregnancy is associated with placental inflammation and adverse outcomes, including stillbirth.

  • 2

    The study examined placental tissue from women with acute COVID-19 placentitis and those recovered from SARS-CoV-2 infection.

  • 3

    No detectable SARS-CoV-2 protein or RNA was found in placental tissue from recovered cases, even with inflammatory lesions present.

  • 4

    Placental injury was observed in cases resulting in stillbirth, but without evidence of ongoing viral infection.

  • 5

    The findings suggest that postacute placental pathology may be due to immune-mediated processes rather than viral persistence.

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