Insulinoma in pregnancy: a case report and literature review of diagnostic challenges, multidisciplinary management, and therapeutic dilemmas - Takeaways - MDSpire

Insulinoma in pregnancy: a case report and literature review of diagnostic challenges, multidisciplinary management, and therapeutic dilemmas

  • By

  • Abdullah Faiz Zaihan

  • Shairyzah Ahmad Hisham

  • Srinivas Siwalinggam

  • Noor Hayatul Al Akmal Noralam

  • Kaeshaelya Thiruchelvam

  • Chia Siang Kow

  • June 3, 2026

  • 0 min

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  • 1

    Insulinoma during pregnancy is rare, with fewer than 30 cases reported, complicating diagnosis due to overlapping symptoms.

  • 2

    A 36-year-old woman presented with recurrent hypoglycaemia at 7 weeks of gestation, later diagnosed with insulinoma via MRI.

  • 3

    Multidisciplinary team management was essential, balancing maternal hypoglycaemia risks with potential fetal harm.

  • 4

    Medical therapy with octreotide was initiated, achieving partial glycaemic control before delivery at 34 weeks due to fetal growth restriction.

  • 5

    Postpartum treatment included endoscopic ultrasound-guided radiofrequency ablation, highlighting challenges in managing larger tumors.

Original Source(s)

Insulinoma in pregnancy: a case report and literature review of diagnostic challenges, multidisciplinary management, and therapeutic dilemmas

  • by Abdullah Faiz Zaihan, Shairyzah Ahmad Hisham, Srinivas Siwalinggam, Noor Hayatul Al Akmal Noralam, Kaeshaelya Thiruchelvam, Chia Siang Kow

  • June 3, 2026

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