The effect of preoperative stellate ganglion block on postoperative delirium in elderly patients undergoing gastrointestinal oncologic surgery: protocol for a randomized, double-blind, sham-controlled trial - Takeaways - MDSpire

The effect of preoperative stellate ganglion block on postoperative delirium in elderly patients undergoing gastrointestinal oncologic surgery: protocol for a randomized, double-blind, sham-controlled trial

  • By

  • Rongrong Song

  • Yuqin Huang

  • Jie Liu

  • Xingyu Wang

  • Yuqian Liu

  • Fanli Wang

  • Fang Wu

  • XiaXia Li

  • Yang Liu

  • Lu Cao

  • Yan Liu

  • Guojieying Wang

  • Minghong Gui

  • Yingbin Wang

  • Xiangfei Huang

  • June 16, 2026

  • 0 min

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  • 1

    Postoperative delirium (POD) occurs in 35%-48% of elderly patients after gastrointestinal surgery, leading to increased morbidity and mortality.

  • 2

    The study aims to evaluate the efficacy of preoperative stellate ganglion block (SGB) in reducing POD incidence and severity.

  • 3

    A total of 174 elderly patients will be randomized to receive either SGB or a sham block before elective gastrointestinal cancer surgery.

  • 4

    Primary outcomes include the cumulative incidence of POD assessed using the 3-Minute Diagnostic Interview for CAM-defined Delirium.

  • 5

    Secondary outcomes will assess delirium severity, postoperative recovery, inflammatory biomarkers, pain trajectories, and hospital stay length.

Original Source(s)

The effect of preoperative stellate ganglion block on postoperative delirium in elderly patients undergoing gastrointestinal oncologic surgery: protocol for a randomized, double-blind, sham-controlled trial

  • by Rongrong Song, Yuqin Huang, Jie Liu, Xingyu Wang, Yuqian Liu, Fanli Wang, Fang Wu, XiaXia Li, Yang Liu, Lu Cao, Yan Liu, Guojieying Wang, Minghong Gui, Yingbin Wang, Xiangfei Huang

  • June 16, 2026

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