Acute acalculous cholecystitis in children due to EBV and cytomegalovirus infection: a rare case report and review of the literature - Takeaways - MDSpire

Acute acalculous cholecystitis in children due to EBV and cytomegalovirus infection: a rare case report and review of the literature

  • By

  • Wenling Ding

  • Renchang Liu

  • June 22, 2026

  • 0 min

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  • 1

    A 7-year-old boy developed acute acalculous cholecystitis during infectious mononucleosis caused by EBV and CMV coinfection.

  • 2

    Symptoms included fever, cervical lymphadenopathy, abdominal pain, and abnormal liver function, with ultrasound showing gallbladder wall thickening.

  • 3

    Diagnosis was confirmed through serological tests showing positive EBV VCA IgM, EBV DNA, and CMV IgM, alongside clinical findings.

  • 4

    The patient was managed conservatively with fasting, intravenous fluids, and antiviral treatment, leading to significant improvement.

  • 5

    This case emphasizes the need to consider viral-associated acute acalculous cholecystitis in children with infectious mononucleosis.

Original Source(s)

Acute acalculous cholecystitis in children due to EBV and cytomegalovirus infection: a rare case report and review of the literature

  • by Wenling Ding, Renchang Liu

  • June 22, 2026

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