Cancer Treatment During Pregnancy and Maternal and Infant Outcomes: A Descriptive Cohort Study Using a Japanese Claims Database - Takeaways - MDSpire
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Cancer Therapy in Pregnancy and Outcomes for Mothers and Infants: A Descriptive Cohort Study Based on Japanese Claims Data

  • By

  • Masami Tsuchiya

  • Tomofumi Ishikawa

  • Takamasa Sakai

  • Satoko Hori

  • Taku Obara

  • October 16, 2026

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  • 1

    This descriptive cohort study used Japanese mother-infant-linked claims data from 2005 through 2024 to characterize cancer treatment and outcomes.

  • 2

    Among 241,891 eligible pregnancies, 500 had a malignant neoplasm diagnosed before delivery and were included in the analytical cohort.

  • 3

    Sixteen pregnancies involved anticancer-agent prescriptions between cancer diagnosis and delivery; 484 were classified as unexposed.

  • 4

    The study described treatment modalities and maternal and infant outcomes, with outcomes stratified by anticancer-agent exposure.

  • 5

    The 236,002 pregnancies without malignant neoplasm diagnoses served as a background benchmark, not a comparator for causal inference.

Original Source(s)

Cancer Treatment During Pregnancy and Maternal and Infant Outcomes: A Descriptive Cohort Study Using a Japanese Claims Database

  • by Masami Tsuchiya, Tomofumi Ishikawa, Takamasa Sakai, Satoko Hori, Taku Obara

  • October 16, 2026

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