Terminated, Withdrawn, or Suspended Suicide Prevention Studies - Takeaways - MDSpire

Terminated, Withdrawn, or Suspended Suicide Prevention Studies

  • By

  • Ian H. Stanley

  • Hannah Libby

  • Julia Finn

  • Lisa M. Horowitz

  • Corey B. Bills

  • June 29, 2026

  • 0 min

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  • 1

    Suicide is a leading cause of death, yet few clinical trials focus on suicidal thoughts and behaviors (STBs).

  • 2

    Of the 1205 registered studies on STBs, 91 (7.6%) were discontinued, with 52 terminated and 35 withdrawn.

  • 3

    Discontinuation reasons included recruitment problems (28.6%), funding issues (19.8%), and COVID-19 interference (7.7%).

  • 4

    No studies reported discontinuation due to participant safety concerns, despite perceptions of heightened risks in suicide-related trials.

  • 5

    Strengthening recruitment and addressing regulatory challenges are essential for expanding the evidence base in suicide prevention research.

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