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1
The nervous system actively regulates oncogenesis, influencing tumor proliferation, invasion, and immune evasion through complex interactions.
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2
Neural signals promote tumor dynamics by modulating inflammation, immunosuppression, and cellular metabolism in hepatocellular carcinoma.
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3
Tumors remodel the peripheral nervous system, inducing axonogenesis and neo-innervation, which facilitates disease progression.
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4
Neuro-tumor crosstalk in hepatocellular carcinoma involves sympathetic, parasympathetic, and sensory innervation affecting tumor development.
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5
Understanding neural mechanisms in cancer is crucial for developing targeted neuromodulatory therapies for hepatocellular carcinoma.