Resolved hyperthyroidism before IVF is not associated with improved cumulative live birth rates: a retrospective cohort study

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The study analyzed IVF outcomes in women with active hyperthyroidism, resolved hyperthyroidism, and normal thyroid function.
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Cumulative live birth rates were significantly lower in the active hyperthyroidism group compared to the normal control group.
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No significant differences in cumulative live birth rates were found between the resolved hyperthyroidism and normal control groups.
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Longer duration of hyperthyroidism was negatively associated with cumulative live birth rates in affected patients.
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The findings suggest that preconception hyperthyroidism adversely affects IVF outcomes.

Frontiers In Endocrinology

by Huizi Jin, Jiejun Luo, Menglu Wu, Yuxuan Fang, Zijin Xu, Lin Zhu, Mingzhu Cao, Zhu Liang, Jing Wang, Yanshan Lin, Yixuan Wu, Wenju Peng, Haiying Liu, Jian-Qiao Liu
June 2, 2026

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