Hybrid data balancing and ensemble learning with SHAP-based explainability to predict cardiovascular disease using a unified dataset - Takeaways - MDSpire
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Predicting Cardiovascular Disease from a Unified Dataset Using Hybrid Data Balancing, Ensemble Learning, and SHAP Explainability

  • By

  • Khandaker Mohammad Mohi Uddin

  • Abdullah

  • Chowdhury Mohammad Rakin Haider

  • October 12, 2026

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  • 1

    The study pooled three publicly available heart disease datasets from Kaggle, UCI, and Cleveland to predict cardiovascular disease.

  • 2

    The authors used Instance Hardness Thresholding and Tomek Links to address class imbalance and noisy class boundaries.

  • 3

    Scaling, balancing, and nested hyperparameter tuning were performed within training folds, with no preprocessing applied to held-out test data.

  • 4

    The study compared 12 classifiers and combined top-performing models using soft- and hard-voting ensembles.

  • 5

    Evaluation included calibration, decision curve analysis, threshold analysis, SHAP explanations, and feature ablation; the authors noted record overlap and no external validation.

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