Bidirectional associations of physical activity and cognitive function in midlife adults: a longitudinal analysis across 26 years follow-up - Takeaways - MDSpire

Bidirectional associations of physical activity and cognitive function in midlife adults: a longitudinal analysis across 26 years follow-up

  • By

  • John J Mitchell

  • Mark Hamer

  • Sarah N James

  • Tom Norris

  • Barbara J Jefferis

  • S Goya Wannamethee

  • Joanna M Blodgett

  • July 3, 2025

  • 0 min

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  • 1

    The study investigates bidirectional associations between physical activity (PA) and cognitive function in midlife over 26 years.

  • 2

    Data from 2888 participants showed that increased verbal memory correlates with higher likelihood of being active in subsequent assessments.

  • 3

    Becoming active was linked to a slight increase in subsequent verbal memory scores, indicating a reciprocal relationship.

  • 4

    Bidirectional associations were found to be stronger for males compared to females, suggesting gender differences in the relationship.

  • 5

    The findings highlight the importance of promoting PA in midlife to potentially enhance cognitive health and mitigate decline.

Original Source(s)

Bidirectional associations of physical activity and cognitive function in midlife adults: a longitudinal analysis across 26 years follow-up

  • by John J Mitchell, Mark Hamer, Sarah N James, Tom Norris, Barbara J Jefferis, S Goya Wannamethee, Joanna M Blodgett

  • July 3, 2025

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