Acute left main coronary artery occlusion with South African flag sign on electrocardiogram: a case report - Takeaways - MDSpire

Acute left main coronary artery occlusion with South African flag sign on electrocardiogram: a case report

  • By

  • Fangming Zhong

  • Baiqing Lin

  • Qifeng Zhang

  • July 8, 2026

  • 0 min

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  • 1

    The South African flag sign (SAFS) on ECG may indicate acute high lateral wall myocardial infarction, typically linked to first diagonal branch occlusion.

  • 2

    A 69-year-old woman with primary hypertension presented with chest pain and SAFS, initially diagnosed with high lateral myocardial infarction.

  • 3

    Emergency coronary angiography revealed a complete occlusion of the left main coronary artery (LMCA) with no collateral flow.

  • 4

    The patient underwent successful percutaneous coronary intervention (PCI), restoring optimal blood flow and leading to an uneventful recovery.

  • 5

    This case highlights the importance of clinical vigilance when interpreting ECG patterns like SAFS, which may indicate severe coronary artery pathology.

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