Case Report: a rare case of small cell carcinoma of the prostate - Takeaways - MDSpire

Case Report: a rare case of small cell carcinoma of the prostate

  • By

  • Kexin Geng

  • Feng Gao

  • June 8, 2026

  • 0 min

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  • 1

    Small cell carcinoma of the prostate is a rare and aggressive malignancy, accounting for 0.5%-2% of prostate cancers.

  • 2

    Early diagnosis of small cell carcinoma is challenging due to non-specific symptoms and normal PSA levels.

  • 3

    A 74-year-old man presented with defecation difficulties and prostate enlargement, leading to a diagnosis of small cell carcinoma.

  • 4

    The patient received chemotherapy but deteriorated rapidly and died despite resuscitation efforts.

  • 5

    This case emphasizes the need for early biopsy in patients with invasive prostate lesions, even with normal PSA levels.

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