Comparative effectiveness of regional analgesia techniques after gastrectomy for gastric cancer: a systematic review and network meta-analysis of randomized trials - Takeaways - MDSpire

Comparative effectiveness of regional analgesia techniques after gastrectomy for gastric cancer: a systematic review and network meta-analysis of randomized trials

  • By

  • Danling Hu

  • Weiwei Cai

  • Anwen Zheng

  • Shuaili You

  • Shan Zhong

  • June 15, 2026

  • 0 min

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  • 1

    Regional analgesia techniques significantly reduce postoperative pain and opioid consumption after radical gastrectomy for gastric cancer.

  • 2

    Intertransverse process plane block (ITPB) notably improves long-term pain at rest and during movement compared to systemic analgesia.

  • 3

    Epidural analgesia (EA) decreases postoperative opioid consumption and enhances the CD4+/CD8+ T-cell ratio, indicating potential immunomodulatory effects.

  • 4

    The evidence for the efficacy of various regional analgesia methods is of low to moderate certainty, necessitating cautious interpretation of findings.

  • 5

    Further high-quality randomized controlled trials are essential to confirm the comparative effectiveness of regional analgesia techniques in this patient population.

Original Source(s)

Comparative effectiveness of regional analgesia techniques after gastrectomy for gastric cancer: a systematic review and network meta-analysis of randomized trials

  • by Danling Hu, Weiwei Cai, Anwen Zheng, Shuaili You, Shan Zhong

  • June 15, 2026

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