Influencing factors of fertility concerns in cancer patients of childbearing age: a systematic review and meta-analysis - Takeaways - MDSpire

Influencing factors of fertility concerns in cancer patients of childbearing age: a systematic review and meta-analysis

  • By

  • Yaxin Wang

  • Renmei Yang

  • Zhaoli Zhang

  • May 18, 2026

  • 0 min

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  • 1

    This systematic review analyzed factors influencing fertility concerns in reproductive-age cancer patients to enhance clinical practice.

  • 2

    The study included 13 articles, comprising 11 cross-sectional and 2 longitudinal studies, with a total of 3282 cancer patients.

  • 3

    Key factors associated with fertility concerns included depression, higher education, fertility intentions, and marital status.

  • 4

    Endocrine therapy and prior fertility counseling were significantly linked to elevated fertility concerns among cancer patients.

  • 5

    The findings highlight the need for targeted interventions to address fertility concerns and improve quality of life in cancer survivors.

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