Resection zone prediction for parenchyma-sparing hepatectomy planning: a comparative study of three modeling paradigms - Takeaways - MDSpire
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Comparing Three Modeling Approaches to Predict Resection Zones for Parenchyma-Sparing Hepatectomy Planning

  • By

  • Janine Rothert

  • Joy Rakshit

  • Judith L. Salz

  • Florentine Huettl

  • Viola Ehses

  • Tobias Huber

  • Hauke Lang

  • Sylvia Saalfeld

  • Georg Hille

  • October 7, 2026

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  • 1

    The study compared distance-based, perfusion-based, and deep learning models for predicting parenchyma-sparing liver resection zones.

  • 2

    The retrospective dataset included 104 patients and 104 resection zones, represented by rasterized segmentation masks at 0.4-mm isotropic resolution.

  • 3

    The mean in silico minimum resection margin was 7.63 ± 6.70 mm, and the distance-based model used an 8-mm tumor dilation.

  • 4

    The distance-based model used liver boundaries and tumor location to predict nonanatomical resections of peripheral tumors.

  • 5

    The perfusion-based model incorporated liver, tumor, and vascular structures and modeled downstream perfusion loss after vessel transections.

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