Comparative Analysis of Coronary CT Angiography and Non-Contrast Thin-Slice CT with Deep Learning for the Detection of Calcified Plaques

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Non-contrast calcium scoring CT is essential for assessing coronary artery disease and quantifying calcium burden in arteries.
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Calcified plaques can be underestimated in CCTA due to artifacts, particularly in low-to-intermediate-risk patients.
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Thin-slice NCCT offers improved spatial resolution over standard calcium scoring CT, enhancing plaque detection.
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The study utilized a deep learning tool for multimodal plaque quantification by aligning CCTA and thin-slice NCCT images.
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This analysis is part of the DISCHARGE trial, which evaluates CCTA's effectiveness compared to invasive coronary angiography.

European Radiology (Springer)

by Kenrick Schulze, Federico Biavati, Bernhard Föllmer, Sotirios Tsogias, Surenjav Chimed, Hanna Balogh, Norbert Nagy, Ferhat Yavuz, Anne-Marieke Stantien, Renad-Heyam Abdelrahman, Steffen Lukas, Maria Bosserdt, Marc Kachelrieß, Wojciech Samek, Marc Dewey
April 20, 2026

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