Mesonephric-like adenocarcinoma of the uterine corpus: a case report - Takeaways - MDSpire

Mesonephric-like adenocarcinoma of the uterine corpus: a case report

  • By

  • Ting Wang

  • Wenlin Yang

  • Xianglun Gong

  • Bing Xue

  • June 5, 2026

  • 0 min

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  • 1

    Mesonephric-like adenocarcinoma (MLA) is a rare subtype of endometrial carcinoma with distinctive morphology and aggressive clinical behavior.

  • 2

    A 60-year-old postmenopausal woman presented with irregular vaginal bleeding and imaging revealed a large uterine mass with deep myometrial invasion.

  • 3

    Histopathological examination showed diverse architectural patterns and immunohistochemical analysis supported the diagnosis of MLA.

  • 4

    MLA is associated with aggressive behavior, including deeper myometrial invasion and higher rates of recurrence compared to mesonephric adenocarcinoma.

  • 5

    Surgical resection is the primary treatment for localized MLA, with combination chemotherapy being the most common adjuvant treatment.

Original Source(s)

Mesonephric-like adenocarcinoma of the uterine corpus: a case report

  • by Ting Wang, Wenlin Yang, Xianglun Gong, Bing Xue

  • June 5, 2026

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