Repeatability of AI-quantified incidental findings on lung cancer screening CT scans in the NELSON trial - Takeaways - MDSpire

Repeatability of AI-quantified incidental findings on lung cancer screening CT scans in the NELSON trial

  • By

  • Stijn Bunk

  • Thijs Bruins Slot

  • Edwin Bennink

  • Grigory Sidorenkov

  • Nils van der Velden

  • Niels Schurink

  • Félix Lades

  • Markus Sebald

  • Marjolein A. Heuvelmans

  • Hester A. Gietema

  • Joachim G. Aerts

  • Geertruida H. de Bock

  • Cornelia Schaefer-Prokop

  • Pim A. de Jong

  • Rozemarijn Vliegenthart

  • Firdaus A. A. Mohamed Hoesein

  • June 17, 2026

  • 0 min

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  • 1

    Lung cancer screening with low-dose CT has reduced mortality but increases radiologists' workload due to incidental findings.

  • 2

    AI methods can automate the measurement of incidental findings, potentially reducing radiologists' workload and interpretive errors.

  • 3

    The study aims to evaluate the repeatability and agreement of AI measurements of incidental findings in lung cancer screening.

  • 4

    Data for the analysis were obtained from the NELSON trial, involving participants aged 50-75 with significant smoking history.

  • 5

    Measurements included aortic diameters, coronary artery calcium volume, vertebral body metrics, and emphysema quantification.

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