Renin and 1-year mortality in critically ill patients with ARDS: trajectories, discrimination, and survival analysis - Takeaways - MDSpire

Renin and 1-year mortality in critically ill patients with ARDS: trajectories, discrimination, and survival analysis

  • By

  • Gabriele Melegari

  • Alessandro Belletti

  • Federica Arturi

  • Antonio Giansante

  • Arianna Gaspari

  • Fabio Gazzotti

  • Elisabetta Bertellini

  • Giovanni Landoni

  • Alberto Barbieri

  • June 23, 2026

  • 0 min

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  • 1

    The study analyzed plasma renin concentration (PRC) and its correlation with 1-year mortality in COVID-19-induced ARDS patients.

  • 2

    104 mechanically ventilated patients with COVID-19-associated ARDS were included, with 46% succumbing within one year.

  • 3

    Elevated renin levels at 72, 120, and 168 hours post-ICU admission were significantly linked to increased 1-year mortality.

  • 4

    Independent predictors of mortality included renin levels at 72 hours, PaO₂/FiO₂ ratio, and procalcitonin levels.

  • 5

    The study suggests that early and serial renin measurements may provide valuable prognostic insights in critically ill ARDS patients.

Original Source(s)

Renin and 1-year mortality in critically ill patients with ARDS: trajectories, discrimination, and survival analysis

  • by Gabriele Melegari, Alessandro Belletti, Federica Arturi, Antonio Giansante, Arianna Gaspari, Fabio Gazzotti, Elisabetta Bertellini, Giovanni Landoni, Alberto Barbieri

  • June 23, 2026

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