Systematic review: digital biomarkers of fatigue in chronic diseases - Takeaways - MDSpire

Systematic review: digital biomarkers of fatigue in chronic diseases

  • By

  • Nana Yaw Aboagye

  • Chloe Hinchliffe

  • Silvia Del Din

  • Wan-Fai Ng

  • Kenneth F. Baker

  • Mark R. Baker

  • October 8, 2025

  • 0 min

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  • 1

    This systematic review examines digital biomarkers and their relationship with fatigue in patients with various chronic diseases.

  • 2

    Fatigue is a prevalent symptom in chronic illnesses, significantly impacting patients' quality of life and daily functioning.

  • 3

    Wearable technologies enable objective measurement of physical activity and physiological signals, aiding in fatigue assessment.

  • 4

    The review analyzed 50 studies involving 5573 participants, highlighting the variability of fatigue across different chronic conditions.

  • 5

    Combining digital biomarkers with self-reported fatigue measures offers a comprehensive approach to managing fatigue in chronic diseases.

Original Source(s)

Systematic review: digital biomarkers of fatigue in chronic diseases

  • by Nana Yaw Aboagye, Chloe Hinchliffe, Silvia Del Din, Wan-Fai Ng, Kenneth F. Baker, Mark R. Baker

  • October 8, 2025

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