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1
Bismuth-containing quadruple therapy achieved a significantly higher eradication rate of 90.36% compared to 74.36% for triple therapy (P = 0.007).
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2
Post-treatment symptom scores for abdominal pain, bloating, and nausea improved more with bismuth-containing quadruple therapy than with triple therapy (P < 0.05).
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3
In patients with successful eradication, bismuth-containing quadruple therapy resulted in lower abdominal pain scores, indicating its potential independent effect on pain relief (P = 0.002).
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4
The incidence of adverse events and medication compliance rates were similar between the bismuth-containing quadruple therapy and triple therapy groups (P > 0.05).
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5
Bismuth-containing quadruple therapy is a promising alternative to triple therapy for treating H. pylori infection in children, with comparable safety and improved efficacy.