Serum vitamin D levels in non-obese women with polycystic ovary syndrome: a systematic review and meta-analysis - Takeaways - MDSpire

Serum vitamin D levels in non-obese women with polycystic ovary syndrome: a systematic review and meta-analysis

  • By

  • Mei Jiang

  • Tan Wang

  • Ling Huang

  • June 16, 2026

  • 0 min

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  • 1

    Vitamin D deficiency is linked to polycystic ovary syndrome (PCOS) and may worsen metabolic disorders like insulin resistance.

  • 2

    This systematic review included 11 studies with 533 non-obese PCOS patients and 574 controls, assessing serum vitamin D levels.

  • 3

    No significant differences in serum 25(OH)D or 1,25(OH)2D levels were found between non-obese PCOS patients and healthy controls.

  • 4

    Heterogeneity in results was attributed to factors like region, diagnostic criteria, BMI, and assay methods.

  • 5

    The study suggests vitamin D deficiency may be more related to obesity than PCOS itself, indicating a need for further research.

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