Prognostic Value of Admission Ionized Calcium for Short-Term Mortality in Critically Ill Children With Sepsis: A Single-Center Retrospective Cohort Study - Takeaways - MDSpire

Prognostic Value of Admission Ionized Calcium for Short-Term Mortality in Critically Ill Children With Sepsis: A Single-Center Retrospective Cohort Study

  • By

  • Chen, Man

  • Feng, Juan

  • Zhang, Zongwei

  • Lv, Xifeng

  • Shi, Ming

  • April 17, 2026

  • 0 min

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  • 1

    Hypocalcemia is prevalent in critically ill pediatric patients with sepsis, affecting 50.8% of the studied cohort.

  • 2

    Lower admission ionized calcium (iCa) levels correlate with increased 28-day mortality in pediatric sepsis patients.

  • 3

    Each 0.1 mmol/L decrease in iCa significantly raises the risk of mortality, with an adjusted hazard ratio of 1.55.

  • 4

    Admission iCa levels provide moderate discrimination for predicting 28-day mortality, with high sensitivity at the threshold.

  • 5

    Incorporating iCa into risk assessments enhances early stratification for critically ill pediatric patients with sepsis.

Original Source(s)

Prognostic Value of Admission Ionized Calcium for Short-Term Mortality in Critically Ill Children With Sepsis: A Single-Center Retrospective Cohort Study

  • by Chen, Man , Feng, Juan , Zhang, Zongwei , Lv, Xifeng , Shi, Ming

  • April 17, 2026

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