The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial - Takeaways - MDSpire

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial

  • By

  • Kai Zhang

  • Run-Qi Guo

  • Shan-Wen Chen

  • Bin Chen

  • Xin-Bo Xue

  • Shan Chen

  • Jian Huang

  • Ming Liu

  • Ye Tian

  • Li Zuo

  • Ming Chen

  • Li-Qun Zhou

  • January 16, 2021

  • 0 min

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  • 1

    The study evaluated the efficacy and safety of Serenoa repens extract (SRE) in treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).

  • 2

    A total of 226 eligible male patients aged 18-50 with CP/CPPS were recruited for this multicenter, randomized, double-blind, placebo-controlled trial.

  • 3

    Participants were randomly assigned to receive either 320 mg of SRE or a placebo daily for 12 weeks, with assessments based on the NIH Chronic Prostatitis Symptom Index.

  • 4

    The primary efficacy endpoint was the change in NIH-CPSI total score, while secondary endpoints included pain, urinary symptoms, and quality of life improvements.

  • 5

    The trial aimed to provide robust evidence for the use of SRE in CP/CPPS, addressing the lack of large-scale studies on this phytotherapeutic agent.

Original Source(s)

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial

  • by Kai Zhang, Run-Qi Guo, Shan-Wen Chen, Bin Chen, Xin-Bo Xue, Shan Chen, Jian Huang, Ming Liu, Ye Tian, Li Zuo, Ming Chen, Li-Qun Zhou

  • January 16, 2021

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