Editorial: Immunosenescence and inflammaging: modulating immune function through diet, lifestyle, and therapeutic interventions - Takeaways - MDSpire

Editorial: Immunosenescence and inflammaging: modulating immune function through diet, lifestyle, and therapeutic interventions

  • By

  • Olivia Briceño

  • Iris P. Guzmán-Guzmán

  • Malén Massot-Cladera

  • June 18, 2026

  • 0 min

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  • 1

    Aging leads to immunosenescence and inflammaging, increasing risks for cancer, autoimmunity, metabolic syndrome, and infections.

  • 2

    Physical activity and immunonutrient supplementation have documented health benefits, but gaps remain in understanding their full impact on elderly populations.

  • 3

    Moderate-intensity exercise improves inflammatory cytokine profiles and insulin sensitivity, supporting its role in immune function modulation.

  • 4

    Mind-body therapies show potential in reducing pro-inflammatory cytokine levels in depression, necessitating further research for effective integration into care.

  • 5

    Molecular mechanisms influencing aging, such as epitranscriptomic modifications, may offer therapeutic targets for age-related dermatological conditions.

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