Circulating biomarkers improve prediction of postoperative outcome after aortic valve surgery

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The study included 492 patients who underwent aortic valve surgery between March 2018 and May 2022.
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Preoperative biomarkers such as hemoglobin, creatinine, and high-sensitivity troponin I were analyzed for their association with postoperative outcomes.
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Logistic regression showed that several biomarkers were independently associated with 30-day mortality after adjusting for EuroSCORE-II.
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Models combining biomarkers with EuroSCORE-II outperformed those using either alone in predicting mortality.
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The findings suggest that integrating biomarkers may enhance decision-making for surgical versus transcatheter aortic valve replacement.

Frontiers In Cardiovascular Medicine

by Till Joscha Demal, Jenny Bialczak, Alina Goßling, Francisco Miguel Ojeda, Oliver Daniel Bhadra, Björn Sill, Johannes Petersen, Sebastian Ludwig, David Grundmann, Lisa Voigtländer, Lara Waldschmidt, Laura Hannen, Niklas Schofer, Stefan Blankenberg, Paulus Kirchhof, Thomas Renné, Lenard Conradi, Hermann Reichenspurner, Evaldas Girdauskas, Andreas Schaefer
June 2, 2026

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