Prevalence, Severity, and Post-Transplant Mortality of Symptomatic Pleural Effusion in Adult Candidates for Liver Transplantation - Takeaways - MDSpire

Prevalence, Severity, and Post-Transplant Mortality of Symptomatic Pleural Effusion in Adult Candidates for Liver Transplantation

  • By

  • Ilker Kolbas

  • Adem Tuncer

  • Emrah Sahin

  • Abuzer Dirican

  • December 27, 2025

  • 0 min

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  • 1

    Symptomatic pleural effusion occurs in 12.8% of adult liver transplant candidates, indicating a significant prevalence among this population.

  • 2

    Patients with symptomatic pleural effusion exhibit more severe liver disease, as evidenced by higher MELD and Child–Pugh scores compared to those without effusion.

  • 3

    Hepatic hydrothorax, a type of symptomatic pleural effusion, is associated with poor prognosis and higher mortality risk in liver transplant candidates.

  • 4

    Liver transplantation is the definitive treatment for refractory hepatic hydrothorax, addressing both portal hypertension and hepatic dysfunction.

  • 5

    Pre-transplant symptomatic pleural effusion is linked to worse short-term post-transplant mortality, highlighting its clinical significance in liver transplant evaluation.

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