Stereotactic Re-irradiation for Recurrence of Breast Cancer in Lymph Nodes

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Lymph node recurrence in breast cancer is linked to poor prognosis and a higher risk of metastatic disease.
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Re-irradiation for locoregional recurrence can be classified into Type 1 and Type 2 based on geometric overlap with prior irradiated volumes.
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Stereotactic body radiotherapy (SBRT) has shown promise in treating nodal recurrence in breast cancer, despite limited data.
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The study at the Oscar Lambret Center evaluated the feasibility and toxicity of SBRT for nodal recurrence in breast cancer.
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Acute and late toxicities were assessed using CTCAE criteria, with primary endpoints focusing on toxicity greater than grade 2.

Bmc Cancer

by Zied Fessi, Salomé Bonnier, Kaoutar Lodyga, Jennifer Wallet, Maël Barthoulot, Chloé Delerue, Pauline Lemoine, Paul Archer, Marie Dworczak, David Pasquier
December 8, 2025

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