Deeply 3D-T1-TFE hypointense voxels are characteristic of phase-rim lesions in multiple sclerosis - Takeaways - MDSpire

Deeply 3D-T1-TFE hypointense voxels are characteristic of phase-rim lesions in multiple sclerosis

  • By

  • Pablo Naval-Baudin

  • Albert Pons-Escoda

  • Àngels Camins

  • Pablo Arroyo

  • Mildred Viveros

  • Josep Castell

  • Mònica Cos

  • Antonio Martínez-Yélamos

  • Sergio Martínez-Yélamos

  • Carles Majós

  • June 6, 2023

  • 0 min

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  • 1

    Multiple sclerosis (MS) is a leading cause of disability in young adults, with clinical courses ranging from benign to rapidly progressive forms.

  • 2

    Recent treatments for secondary progressive MS (SPMS) emphasize the need for early detection of disease progression through imaging.

  • 3

    Phase-rim lesions (PRLs) and slowly expanding lesions (SELs) are potential imaging markers for progressive MS, linked to worse clinical outcomes.

  • 4

    PRLs are characterized by deep hypointensity on T1-weighted imaging, particularly visible on advanced 3D T1 sequences.

  • 5

    Standard MRI protocols often miss PRLs, necessitating the use of susceptibility-weighted imaging for accurate detection.

Original Source(s)

Deeply 3D-T1-TFE hypointense voxels are characteristic of phase-rim lesions in multiple sclerosis

  • by Pablo Naval-Baudin, Albert Pons-Escoda, Àngels Camins, Pablo Arroyo, Mildred Viveros, Josep Castell, Mònica Cos, Antonio Martínez-Yélamos, Sergio Martínez-Yélamos, Carles Majós

  • June 6, 2023

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