Variations in Ocular Surface Metrics Among Patients with Lacrimal Duct Obstruction at Different Locations - Takeaways - MDSpire
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Variations in Ocular Surface Metrics Among Patients with Lacrimal Duct Obstruction at Different Locations

  • By

  • Xiao-lin Zhang

  • Jia-yin Chen

  • Meng-ru Li

  • Ya-li Liu

  • Hui-min Zhang

  • Jiang-Wei Fu

  • Min Hu

  • December 2, 2025

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  • 1

    Lacrimal duct obstruction (LDO) is a common cause of epiphora, linked to inflammatory responses and idiopathic fibrosis.

  • 2

    Dry eye syndrome, prevalent in ophthalmology, can result from LDO, affecting tear quality and ocular surface stability.

  • 3

    This study analyzed ocular surface metrics in 74 LDO patients, categorized by obstruction site: upper and lower lacrimal canaliculus.

  • 4

    Significant differences in non-invasive tear breakup time (NIBUT) and ocular staining scores (OSS) were found between the two LDO groups.

  • 5

    Statistical analysis utilized SPSS software, with P < 0.05 considered significant for intergroup comparisons.

Original Source(s)

Variations in Ocular Surface Metrics Among Patients with Lacrimal Duct Obstruction at Different Locations

  • by Xiao-lin Zhang, Jia-yin Chen, Meng-ru Li, Ya-li Liu, Hui-min Zhang, Jiang-Wei Fu, Min Hu

  • December 2, 2025

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