The impact of statin therapy on the prognosis of hormone receptor-positive breast cancer: a systematic review and meta-analysis - Takeaways - MDSpire

The impact of statin therapy on the prognosis of hormone receptor-positive breast cancer: a systematic review and meta-analysis

  • By

  • Xiaowen Ma

  • Yiming Sun

  • Yaqin Qi

  • Hiajiang Qu

  • Feng Zhang

  • June 3, 2026

  • 0 min

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  • 1

    Statin therapy is associated with a 23% reduction in recurrence risk in hormone receptor-positive breast cancer patients.

  • 2

    The meta-analysis included 7 studies with a total of 267,913 HR+ breast cancer patients.

  • 3

    Statin use significantly decreases mortality in HR+ breast cancer, with a hazard ratio of 0.77.

  • 4

    Findings suggest statins may serve as an effective adjunctive therapy for HR+ breast cancer patients.

  • 5

    Future large-scale, prospective trials are necessary to optimize the clinical applications of statins in breast cancer.

Original Source(s)

The impact of statin therapy on the prognosis of hormone receptor-positive breast cancer: a systematic review and meta-analysis

  • by Xiaowen Ma, Yiming Sun, Yaqin Qi, Hiajiang Qu, Feng Zhang

  • June 3, 2026

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