Intrapericardial Triamcinolone Instillation for Recurrent Pericardial Effusion in Pediatric Patients: A Review of Efficacy and Safety - Takeaways - MDSpire

Intrapericardial Triamcinolone Instillation for Recurrent Pericardial Effusion in Pediatric Patients: A Review of Efficacy and Safety

  • By

  • Abhiram Reddy

  • Daniel Peck

  • Daniel Cortez

  • Bibhuti Das

  • John Bass

  • Varun Aggarwal

  • May 27, 2026

  • 0 min

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  • 1

    Recurrent pericardial effusion in children is challenging to manage and often requires further drainage or therapy after initial resolution.

  • 2

    Intrapericardial triamcinolone has shown efficacy in adults and was previously effective in reducing pediatric post-surgical effusions.

  • 3

    The study involved nine pediatric patients who received intrapericardial triamcinolone from 2015 to 2025 at the University of Minnesota.

  • 4

    Cytological and microbiological testing of pericardial fluid in patients revealed elevated protein and LDH levels, but no malignant cells.

  • 5

    The median age of patients at triamcinolone instillation was 21.5 months, with treatment administered after a median of 22.5 days post-initial drainage.

Original Source(s)

Intrapericardial Triamcinolone Instillation for Recurrent Pericardial Effusion in Pediatric Patients: A Review of Efficacy and Safety

  • by Abhiram Reddy, Daniel Peck, Daniel Cortez, Bibhuti Das, John Bass, Varun Aggarwal

  • May 27, 2026

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