Discrimination of sustained VT in structural heart disease using LGE-CMR and computational simulation: moving beyond LVEF - Takeaways - MDSpire

Discrimination of sustained VT in structural heart disease using LGE-CMR and computational simulation: moving beyond LVEF

  • By

  • Kun Zuo

  • Kuibao Li

  • Lucheng Xu

  • Yiming Wang

  • Shiwei Lu

  • Zhaokai Kong

  • Zhenyin Fu

  • Jianjun Zhang

  • Ruiqing Dong

  • Ling Xia

  • Dongdong Deng

  • Zheng Liu

  • July 7, 2026

  • 0 min

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  • 1

    Sustained ventricular tachycardia (VT) is a significant cause of sudden cardiac death in patients with structural heart disease (SHD).

  • 2

    The study developed an integrated model combining late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) with computational VT simulation.

  • 3

    Among 82 patients, lower left ventricular ejection fraction (LVEF) and visual LGE positivity were associated with sustained VT.

  • 4

    The LGE-VTsim index effectively discriminated sustained VT with a C-statistic of 0.816, surpassing LVEF as a risk marker.

  • 5

    The study highlights the limitations of LVEF alone in risk stratification for sustained VT in patients with SHD.

Original Source(s)

Discrimination of sustained VT in structural heart disease using LGE-CMR and computational simulation: moving beyond LVEF

  • by Kun Zuo, Kuibao Li, Lucheng Xu, Yiming Wang, Shiwei Lu, Zhaokai Kong, Zhenyin Fu, Jianjun Zhang, Ruiqing Dong, Ling Xia, Dongdong Deng, Zheng Liu

  • July 7, 2026

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