Correction: Overcoming chemoresistance in esophageal cancer with synergistic strategies - Takeaways - MDSpire

Correction: Overcoming chemoresistance in esophageal cancer with synergistic strategies

  • By

  • Chunxiao Gao

  • Ting Zhang

  • Guangyuan Li

  • Weishan Zhang

  • Honglin Chen

  • Diefei Li

  • Jixuan Xu

  • Mengxue Li

  • Ruihong Wang

  • Yamin Xing

  • Jian Zhan

  • Zhentai Ren

  • Xia Xue

  • Wulong Liang

  • Xiangdong Sun

  • Xiaojuan Zhang

  • Xinfeng Liang

  • Hongqiao Zhan

  • Zisen Zhang

  • Xiufeng Chu

  • July 3, 2026

  • 0 min

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  • 1

    The article corrects a mistake regarding the role of chemotherapy in combination therapies for esophageal cancer.

  • 2

    CD8+ T cells are functionally impaired in esophageal cancer due to immune checkpoint molecules and M2-type tumor-associated macrophages.

  • 3

    P-gp inhibitors like Encequidar and MB07133 show promise in overcoming chemoresistance, though trials in esophageal cancer are lacking.

  • 4

    Elevated expression of DNA damage response proteins is linked to chemotherapy resistance in esophageal cancer.

  • 5

    CDK4/6 inhibitors are being explored for their efficacy in esophageal cancer, with ongoing clinical trials for Palbociclib.

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