Artificially Sweetened and Sugar-Sweetened Beverage Intake and Risk of Liver Cancer - Takeaways - MDSpire

Artificially Sweetened and Sugar-Sweetened Beverage Intake and Risk of Liver Cancer

  • By

  • Cody Z. Watling

  • Longgang Zhao

  • Xinyuan Zhang

  • Emily Deubler

  • Amparo G. Gonzalez-Feliciano

  • Barry I. Graubard

  • Jessica L. Petrick

  • Aika Wojt

  • Gisela Butera

  • Jonathan N. Hofmann

  • Laura E. Beane Freeman

  • Martha J. Shrubsole

  • Wei Zheng

  • Staci L. Sudenga

  • Eva Schernhammer

  • A. Heather Eliassen

  • Lorelei A. Mucci

  • Howard D. Sesso

  • Rashmi Sinha

  • Erikka Loftfield

  • Caroline Y. Um

  • Marjorie L. McCullough

  • Mazda Jenab

  • Xuehong Zhang

  • Katherine A. McGlynn

  • June 10, 2026

  • 0 min

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  • 1

    Liver cancer is projected to increase by 55% globally by 2040, with over 42,000 new cases expected in the US by 2025.

  • 2

    Aspartame has been classified as a group 2B carcinogen by IARC, indicating a possible link between artificially sweetened beverages and liver cancer.

  • 3

    Intake of sugar-sweetened beverages is associated with health issues like obesity and diabetes, which are risk factors for liver cancer.

  • 4

    A pooled analysis of 11 prospective cohort studies aimed to investigate the relationship between beverage intake and liver cancer risk.

  • 5

    The study utilized validated food frequency questionnaires to assess beverage intake and linked cancer diagnoses to registries for accuracy.

Original Source(s)

Artificially Sweetened and Sugar-Sweetened Beverage Intake and Risk of Liver Cancer

  • by Cody Z. Watling, Longgang Zhao, Xinyuan Zhang, Emily Deubler, Amparo G. Gonzalez-Feliciano, Barry I. Graubard, Jessica L. Petrick, Aika Wojt, Gisela Butera, Jonathan N. Hofmann, Laura E. Beane Freeman, Martha J. Shrubsole, Wei Zheng, Staci L. Sudenga, Eva Schernhammer, A. Heather Eliassen, Lorelei A. Mucci, Howard D. Sesso, Rashmi Sinha, Erikka Loftfield, Caroline Y. Um, Marjorie L. McCullough, Mazda Jenab, Xuehong Zhang, Katherine A. McGlynn

  • June 10, 2026

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