Risk factor analysis investigating the use of potentially inappropriate medications

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Polypharmacy is prevalent among older adults and is associated with the use of potentially inappropriate medications (PIMs).
2

Age positively correlates with the number of prescribed medications, with a correlation coefficient of 0.476 (p < 0.0001).
3

Proton pump inhibitors were identified as the most commonly prescribed PIMs among the study participants.
4

Patients prescribed at least one PIM consulted significantly more medical facilities than those without PIMs (p < 0.0001).
5

Independent risk factors for PIM use include age, hypertension, gastrointestinal disorders, and neuropsychiatric disorders.

Frontiers In Medicine

by Ryo Nonaka, Hatsuho Ejima, Saki Nakayama, Yuiko Suzuki, Yurika Hirota, Emiko Kurosawa, Shigeto Mashiko, Atsuhiro Kanno, Katsutoshi Furukawa
July 8, 2026

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