Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling - Takeaways - MDSpire

Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling

  • By

  • Tenghuan Wang

  • Na Xing

  • Huixin Li

  • Yuanyuan Mao

  • Dan Cheng

  • Yanan He

  • Sheng Guan

  • May 29, 2026

  • 0 min

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  • 1

    This trial compared desflurane with ciprofol, esketamine, or saline in patients undergoing endovascular coiling for intracranial aneurysms.

  • 2

    Neurocognitive recovery improved significantly over time across all groups, with no significant differences in recovery trajectories.

  • 3

    The incidence of postoperative nausea and vomiting was significantly lower in the ciprofol group compared to the other groups.

  • 4

    Ciprofol also resulted in the lowest incidence of dizziness and metoclopramide requirement among the anesthetic regimens.

  • 5

    Desflurane plus esketamine provided superior analgesia compared to desflurane plus ciprofol in postoperative pain management.

Original Source(s)

Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling

  • by Tenghuan Wang, Na Xing, Huixin Li, Yuanyuan Mao, Dan Cheng, Yanan He, Sheng Guan

  • May 29, 2026

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