Risk calculator of multimorbid risk of rehospitalization and death from heart failure: including the contribution of the gut microbiome

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A novel 11-variable risk model for heart failure (HF) was developed, incorporating multimorbidity and gut microbiome factors.
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The model demonstrated a diagnostic performance of 0.71 in the training cohort and 0.70 in the validation cohort.
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Patients were categorized into low-, mid-, and high-risk groups, with higher risk correlating with increased incidence of death or rehospitalization.
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The study utilized two independent HF cohorts, combining data to enhance the robustness of the risk model.
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This risk assessment tool addresses the limitations of current HF risk scores by including the impact of comorbidities and gut microbiome.

European Journal Of Preventive Cardiology

by Muhammad Zubair Israr, Andrea Salzano, Hong Zhan, Adriaan A Voors, Leong L Ng, Toru Suzuki
April 28, 2025

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