Associations between adjuvant antibiotic therapy and fistula formation after incision and drainage of anorectal abscesses: results from a retrospective cohort study - Takeaways - MDSpire

Associations between adjuvant antibiotic therapy and fistula formation after incision and drainage of anorectal abscesses: results from a retrospective cohort study

  • By

  • J. Alabbad

  • S. Almutairi

  • N. Alsabagha

  • H. Alhamly

  • F. Alnaqi

  • December 24, 2025

  • 0 min

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  • 1

    Adjuvant antibiotic therapy was evaluated for its effect on fistula formation after incision and drainage of anorectal abscesses.

  • 2

    The study included 770 adult patients, with 60.5% receiving adjuvant antibiotics and an overall fistula rate of 6.8%.

  • 3

    No significant differences in fistula formation rates or time to diagnosis were found between patients with and without antibiotic therapy.

  • 4

    Fistula formation was linked to abscess location, age over 40 years, and intersphincteric abscess, while diabetes showed a negative association.

  • 5

    The study concluded that adjuvant antibiotic therapy does not reduce the risk of fistula formation following abscess incision and drainage.

Original Source(s)

Associations between adjuvant antibiotic therapy and fistula formation after incision and drainage of anorectal abscesses: results from a retrospective cohort study

  • by J. Alabbad, S. Almutairi, N. Alsabagha, H. Alhamly, F. Alnaqi

  • December 24, 2025

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