Prevalence of Injection-Related Bacterial and Fungal Infection Among People Who Inject Drugs: A Systematic Review and Meta-analysis - Takeaways - MDSpire

Prevalence of Injection-Related Bacterial and Fungal Infection Among People Who Inject Drugs: A Systematic Review and Meta-analysis

  • By

  • Alice Wheeler

  • Jeffrey Masters

  • Alyssa Pradhan

  • Jess Monineath Roth

  • Louisa Degenhardt

  • Gregory J Dore

  • Gail V Matthews

  • Evan B Cunningham

  • Amy Peacock

  • Samantha Colledge-Frisby

  • Jason Grebely

  • Behzad Hajarizadeh

  • Marianne Martinello

  • February 24, 2025

  • 0 min

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  • 1

    Injection-related bacterial and fungal infections are a significant health issue among people who inject drugs (PWID).

  • 2

    The systematic review identified 87 eligible studies, revealing varying prevalence rates of injection-related infections across different time frames.

  • 3

    Skin and soft-tissue infections had a lifetime prevalence of 47%, while endocarditis and bloodstream infections had lower prevalence rates.

  • 4

    Hospitalization rates for injection-related infections among PWID are increasing, leading to higher healthcare costs.

  • 5

    There is a critical need for updated reviews to monitor the burden of injection-related infections and target high-risk subpopulations.

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