Quantitative ultrashort echo time (UTE) magnetic resonance imaging of femoral trabecular bone in aging and osteoporosis - Takeaways - MDSpire
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Quantitative Ultrashort Echo-Time MRI of Femoral Trabecular Bone in Aging and Osteoporosis

  • By

  • Jisook Yi

  • Arya Suprana

  • Yankai Meng

  • Yajun Ma

  • Eric Chang

  • Gina Woods

  • Charles Ginsberg

  • Saeed Jerban

  • Jiang Du

  • October 7, 2026

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  • 1

    DXA measures areal bone mineral density but does not directly visualize trabecular architecture, while QCT measures volumetric density using ionizing radiation.

  • 2

    This prospective, single-center study evaluated quantitative 3-dimensional UTE MRI of proximal femoral trabecular bone in adult female volunteers.

  • 3

    The final cohort included 92 women aged 20 to 83 years, classified as young normal, old normal, osteopenia, or osteoporosis.

  • 4

    Dual-echo PD-UTE and STAIR-UTE sequences provided signals used to calculate pore-to-matrix ratio and matrix index as trabecular biomarkers.

  • 5

    UTE MRI can directly image bone and assess bound water in trabecular bone without ionizing radiation, addressing limitations of conventional MRI and X-ray-based methods.

Original Source(s)

Quantitative ultrashort echo time (UTE) magnetic resonance imaging of femoral trabecular bone in aging and osteoporosis

  • by Jisook Yi, Arya Suprana, Yankai Meng, Yajun Ma, Eric Chang, Gina Woods, Charles Ginsberg, Saeed Jerban, Jiang Du

  • October 7, 2026

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