Adjunctive Semaglutide in Patients Undergoing Intragastric Balloon for Weight Loss: 12-Month Prospective Comparative Study - Takeaways - MDSpire

Adjunctive Semaglutide in Patients Undergoing Intragastric Balloon for Weight Loss: 12-Month Prospective Comparative Study

  • By

  • Khaled E. Barakat

  • Doaa K. Abuhasan

  • Mohamed F. Asal

  • Ahmed Adham R. Elsayed

  • Mohamed R. Mahmoud

  • Madeline Guy

  • Rama Safadi

  • Marc D. Basson

  • November 10, 2025

  • 0 min

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  • 1

    Obesity is a global health crisis, with rates doubling in the past 35 years, necessitating effective management strategies.

  • 2

    Intragastric balloons (IGBs) provide a less invasive weight loss option, but their efficacy combined with semaglutide remains unclear.

  • 3

    Semaglutide is an effective GLP-1 receptor agonist approved for weight management in adults with obesity or overweight.

  • 4

    This study randomized participants to receive either IGB alone or IGB with semaglutide to evaluate combined weight loss efficacy.

  • 5

    The semaglutide dosing regimen was designed to optimize weight loss effects while minimizing adverse effects during IGB placement.

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