Fecal and Sputum Microbiota and Treatment Response in Patients With Mycobacterium abscessus Pulmonary Disease - Takeaways - MDSpire

Fecal and Sputum Microbiota and Treatment Response in Patients With Mycobacterium abscessus Pulmonary Disease

  • By

  • Joong-Yub Kim

  • Sujin An

  • So Yeon Kim

  • Eunhye Bae

  • Yong-Joon Cho

  • Nakwon Kwak

  • Donghyun Kim

  • Jae-Joon Yim

  • November 5, 2024

  • 0 min

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  • 1

    The study identified microbial signatures in fecal and sputum samples linked to treatment response in Mycobacterium abscessus pulmonary disease.

  • 2

    Fecal microbiota diversity decreased significantly in early treatment responders compared to nonresponders at 2 weeks.

  • 3

    Increased Eubacterium hallii in baseline fecal microbiota indicated unresponsiveness, while Enterococcus abundance at 2 weeks correlated with favorable outcomes.

  • 4

    High baseline levels of Burkholderia-Caballeronia-Paraburkholderia and Porphyromonas in sputum were associated with good treatment response.

  • 5

    Changes in microbial diversity and composition reflect treatment response in patients with Mycobacterium abscessus pulmonary disease.

Original Source(s)

Fecal and Sputum Microbiota and Treatment Response in Patients With Mycobacterium abscessus Pulmonary Disease

  • by Joong-Yub Kim, Sujin An, So Yeon Kim, Eunhye Bae, Yong-Joon Cho, Nakwon Kwak, Donghyun Kim, Jae-Joon Yim

  • November 5, 2024

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