Growth-adjusted reference values for the main pulmonary artery-to-ascending aorta ratio derived from clinically indicated chest CT in children - Takeaways - MDSpire

Growth-adjusted reference values for the main pulmonary artery-to-ascending aorta ratio derived from clinically indicated chest CT in children

  • By

  • Ying Lyu

  • Mingshu Yang

  • Huaqin Bu

  • Chao Gong

  • Jinhua Ma

  • Tingting Luo

  • Li Zhong

  • Yongle Zhao

  • Xiao Yang

  • Ting Wang

  • Yan Chen

  • Daiyin Tian

  • July 18, 2026

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  • 1

    The study aims to derive growth-adjusted reference values for the main pulmonary artery-to-ascending aorta ratio in pediatric patients.

  • 2

    Current pediatric guidelines rely on absolute MPA/AA thresholds, which do not account for age and body size variations.

  • 3

    The modeling cohort included children under 18 years who underwent clinically indicated chest CT examinations without known pulmonary conditions.

  • 4

    An independent RHC cohort was established to validate the association between growth-adjusted MPA/AA values and invasive hemodynamic data.

  • 5

    CT examinations were performed using various scanners, ensuring reliable measurement of both the MPA and AA for accurate analysis.

Original Source(s)

Growth-adjusted reference values for the main pulmonary artery-to-ascending aorta ratio derived from clinically indicated chest CT in children

  • by Ying Lyu, Mingshu Yang, Huaqin Bu, Chao Gong, Jinhua Ma, Tingting Luo, Li Zhong, Yongle Zhao, Xiao Yang, Ting Wang, Yan Chen, Daiyin Tian

  • July 18, 2026

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