Factors associated with local failure after stereotactic radiation to the surgical bed of patients with a single breast cancer metastasis - Takeaways - MDSpire

Factors associated with local failure after stereotactic radiation to the surgical bed of patients with a single breast cancer metastasis

  • By

  • Ory Haisraely

  • Marcia L. Jaffe

  • Yaacov R Lawrence

  • Zvi Symon

  • Anton Whol

  • Thaila Kaisman-Elbaz

  • Zvi R Cohen

  • Alicia Taliansky

  • Orit Kaidar-Person

  • April 22, 2025

  • 0 min

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  • 1

    Metastatic breast cancer is increasingly associated with brain metastases due to improved survival rates in breast cancer patients.

  • 2

    Local therapy for breast cancer brain metastases has shifted towards stereotactic radiation, reducing the use of whole brain radiation.

  • 3

    Factors influencing local control after stereotactic radiation include tumor histology, molecular subtype, and surgical cavity characteristics.

  • 4

    The study evaluated 62 patients with single breast cancer brain metastasis treated with stereotactic radiation post-craniotomy.

  • 5

    Most patients in the cohort were HER2 positive, with a significant portion having stable receptor status after treatment.

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