COVID-19 Vaccination in Pregnancy: Efficacy of Second-Generation Vaccines, Maternal-Neonatal Safety, and Strategies to Address Vaccine Hesitancy - Takeaways - MDSpire

COVID-19 Vaccination in Pregnancy: Efficacy of Second-Generation Vaccines, Maternal-Neonatal Safety, and Strategies to Address Vaccine Hesitancy

  • By

  • Xu, Jia

  • Liu, Fang

  • Yuan, Han-Ying

  • Pan, Heng

  • Xi, Xuan

  • Chen, Che

  • Li, De-Hong

  • LU, Yan

  • May 22, 2026

  • 0 min

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  • 1

    Pregnant women are at increased risk for severe COVID-19, leading to higher ICU admissions and maternal mortality.

  • 2

    Physiological changes during pregnancy worsen respiratory function, increasing vulnerability to SARS-CoV-2.

  • 3

    Despite evidence supporting the safety and efficacy of COVID-19 vaccines, vaccine hesitancy persists among pregnant women.

  • 4

    The review focuses on second-generation COVID-19 vaccines and their impact on maternal and neonatal health outcomes.

  • 5

    Barriers to vaccine uptake must be addressed to ensure equitable access and effective vaccination strategies for pregnant women.

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