Preoperative proteinuria correlates with renal function after partial nephrectomy for renal cell carcinoma - Takeaways - MDSpire

Preoperative proteinuria correlates with renal function after partial nephrectomy for renal cell carcinoma

  • By

  • Michele Nicolazzini

  • Carlotta Palumbo

  • Francesca Porté

  • Gianmarco Bondonno

  • Paolo De Angelis

  • Maria Teresa Del Galdo

  • Alessandro Volpe

  • June 20, 2024

  • 0 min

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  • 1

    Preoperative proteinuria is associated with a higher incidence of chronic kidney disease (CKD) after partial nephrectomy for renal cell carcinoma (RCC).

  • 2

    Patients with preoperative proteinuria had consistently lower mean eGFR values post-surgery compared to those without proteinuria.

  • 3

    Lower baseline eGFR is identified as an independent predictor of CKD stage III or higher after nephrectomy.

  • 4

    The study included 295 patients, with 7.4% presenting preoperative proteinuria, highlighting its relevance in renal function outcomes.

  • 5

    Older age and lower baseline eGFR were significant predictors of CKD progression, while preoperative proteinuria's predictive value remains debated.

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